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Resistance of Aedes aegypti (Diptera: Culicidae) in 2006 to pyrethroid insecticides in Indonesia and its association with oxidase and esterase levels

Ahmad I.a, Astari S.a, Tan M.a

a Physiology, Developmental Biology and Biomedical Research Group, School of Life Sciences and Technology, Bandung Institute of Technology, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]Three strains of Aedes aegypti collected in 2006 from three major cities in Indonesia, i.e., Bandung, Palembang and Surabaya, were tested to determine their resistance status to pyrethroid (permethrin and deltamethrin) and also the resistance mechanisms regarding three detoxifying enzymes, i.e., oxidase, esterase A and esterase B. The resistance level was expressed as Resistance Ratio (RR) compared to the susceptible VCRU strain. Results of this study showed that Ae. aegypti in Indonesia has developed tolerance to permethrin and deltamethrin, except in the Bandung strain, which was resistant to permethrin and deltametherin with RR90 79.3 and 23.7, respectively. The study also suggested that detoxifying enzymes (oxidase, esterase A and esterase B) apparently were involved in the development of resistance in Bandung strain as indicated by the high level of activity of those enzymes in Bandung strain compared to other more susceptible strains. Although there is a possibility that other mechanisms, such as a target-site resistance mechanism, in Bandung strain were also involved. © 2007 Asian Network for Scientific Information.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Aedes aegypti,Esterase,Indonesia,Oxidases,Pyrethroids,Resistance[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.3923/pjbs.2007.3688.3692[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]