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The antibiotic potency of amoxicillin-clavulanate co-crystal
a Crystallography and Technology Pharmacy Laboratory, School of Pharmacy, Institute Technology Bandung, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]The antibiotic activity related to compositions of amoxicillin-clavulanate co-crystals heated compare to the physical mixtures against non-betalactam bacteria: Sarcina lutea sp. has been studied. Amoxicillin trihydrate-potassium clavulanate were mixed in molar ratios: 0:10; 1:9; 2:8; until to 10:0 and heated at 50°C along 30 min. Inhibition diameters of the co-crystals were compared to amoxicillin heated and inhibition diameters of the physical mixtures were compared to amoxicillin raw material as counterparts. The results showed the tendency of increasing potency of the co-crystals in molar ratios 3:7-3:7 with significantly, improvement at molar ratios 4:6; 6:4; 8:2 and 9:1 which proved different profile from the physical mixture. © 2007 Asian Network for Scientific Information.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Amoxicillin,Antibiotic potency,Clavulanate,Co-erystal,DSC,Non beta lactamase,Sarcina lutea sp.,SEM,XR.PD[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.3923/ijp.2007.475.481[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]