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Knowledge based system for supporting genomic based personalized medicine

Winda Astari R.a, Ayuningtyas C.H.a, Putri Saptawati G.A.a

a School of Electrical Engineering and Informatics, Bandung Institute of Technology, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]Single Nucleotide Polymorphisms (SNP) is one of some types of genetic variations in human’s DNA. SNP can be related to risk of disease’s emergence and/or specific body’s response to certain medicine. SNP has been used to analyse disease’s emergence and body’s response to medicine in some commercial direct-to-consumer (DTC) DNA test. But, based on research conducted by United States Government Accountability Office (GAO), the result of DTC DNA tests was questionable. Therefore, we offer to develop a knowledge based system for analyzing human’s SNP. The knowledge based will use validated SNP public database as the knowledge base. The knowledge based was implemented using MySQL database and the knowledge based system application was built using PHP language. Inference method used in the application was implemented using hypothesize and test method. © 2011 IEEE.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Disease diagnosis,DNA tests,Genetic variation,Government accountability offices,Inference methods,Knowledge base,MySQL database,Personalized medicines,Public database,Single nucleotide polymorphisms,Test method[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]disease diagnosis,knowledge based system,personalized medicine,Single Nucleotide Polymorphism[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.1109/ICEEI.2011.6021610[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]