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Characterization and identification of a soil Nocardia sp. TP-1 isolated from Indonesian volcanic soil
Andayani D.G.S.a, Sukandar E.Y.a, Sukandar U.a, Ketut Adnyana I.a
a School of Pharmacy, Bandung Institute of Technology, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]Tangkuban Perahu mountain in West Java was one of volcanic mountain in Indonesia. Volcanic soil contained some unique minerals that microorganism need for producing their secondary metabolite. TP-1 strain is a soil microbe, isolated from soil taken from the area in Tangkuban Perahu mountain Since the secondary metabolite of Nocardia sp. can combat pathogen resistant bacteria, fungi and cell line cancer so it can be applied in pharmaceutical industries. The objective of this research is identified and characterized actinomycetes that have potency to produce secondary metabolite for further utilization in pharmacy. The methods are by analyze of its morphological, physiological, biochemical and molecular characteristics of TP-1 strain. The results of analysis of its morphological, physiological, and biochemical characteristics strongly suggested that TP-1 strain belonged to the Nocardia sp. Analysis of the nucleotide sequence of the 16S rRNA gene of Nocardia sp. TP-1 strain showed a strong similarity (90%) with the 16S rRNA gene of Nocardia sp. YIM 65630. Conidia, usually round, chalk, and white light grey. It is a new information that Nocardia sp. can produce some secondary metabolites like antibacterial, antifungal and anticancer activity.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Biochemical and molecular identification,Homology,Morphological,Nocardia sp. YIM 65630 TP-1,Physiological[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]