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Oligostilbenoids from Vatica pauciflora and the oxidative effect on chang cells
Kamarozaman A.S.a, Latip J.b, Syah Y.M.c, Rajab N.b, Jaloh A.b
a Centre of Foundation Studies, MARA University of Technology, Puncak Alam Campus, Malaysia
b Department of Chemical Sciences and Food Technology, Faculty of Sciences and Technology, National University of Malaysia, Malaysia
c Department of Chemistry, Faculty of Mathematics and Natural Sciences, Bandung Institute of Technology, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]Phytochemical studies on the woods and twigs of Vatica pauciflora (Dipterocarpaceae) have been conducted. The woods and twigs of V. pauciflora were extracted in methanol and ethanol respectively with Soxhlet apparatus. The crude methanol extracts from the woods were semi-purified by vacuum liquid chromatography to give 14 fractions (VMB01-VMB14). The VMB10 was further purified by radial chromatography to give pure dimmer stilbenoid. The same technique has been employed on the crude ethanol extracts from the twigs in which one pure fraction, VER612 was obtained. Based on the UV, IR, NMR and mass spectral data, the pure compounds were characterized as ε-viniferin and vaticanol G respectively. An oxidative damage test which was done on Chang liver cells has shown that ε-viniferin has a potential to be a chemopreventive agent to protect liver cells from oxidative damage. © IOP Publishing Ltd 2013.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Chemopreventive,Chemopreventive agents,Dipterocarpaceae,Mass spectral data,Oxidative damage,Radial chromatography,Soxhlet apparatus,Vatica pauciflora[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Vatica pauciflora,Vaticanol G and chemopreventive,ε-viniferin[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.1088/1742-6596/423/1/012045[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]