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Inflammatory cell extraction and nuclei detection in pap smear images

Riana D.a, Plissiti M.E.b, Nikou C.b, Widyantoro D.H.a, Mengko T.L.R.a, Kalsoem O.c

a Bandung Institute of Technology, Bandung, Indonesia
b Department of Computer Science and Engineering, University of Ioannina, Ioannina, Greece
c Veteran Bandung Laboratory of Pathology, Bandung, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]The automated diagnosis of cervical cancer in Pap smear images is a difficult though extremely important procedure. In order to obtain reliable diagnostic information, the nuclei and their characteristics must be correctly identified and evaluated. However, the presence of inflammatory and overlapping cells in these images complicates the detection process. In this work, a segmentation algorithm is developed to extract the inflammatory cells and enable accurate nuclei detection. The proposed algorithm is based on the combination of gray level thresholding and the definition of a distance rule, which entails in the identification of inflammatory cells. The results indicate that our method significantly simplifies the nuclei detection process, as it reduces the number of inflammatory cells that may interfere.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Cytoplasm segmentation,Inflammatory cells,Nucleus detection,Pap smear images,Thresholding[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text]Dwiza Riana would like to thank Directorate General of Higher Education-Ministry of Education and Culture, (DIKTI), Indonesia through BPPS (2011), DGHE Sandwich Program (2013) and Doctoral Dissertation Research (2014) for generous scholarship, Laboratorium Patologi Veteran Bandung, Indonesia for the database Pap smear images and University of Ioannina, Greece for location of DGHE Sandwich Program.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.4018/IJEHMC.2015040103[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]