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Preparation and characterization of magnetic carbonate apatite/chitosan/alginate composite scaffold

Indrani D.J.a, Purwasasmita B.S.b, Adi W.A.c, Simanjuntak J.a

a Department of Dental Materials Science, University of Indonesia, Jakarta, Indonesia
b Engineering Physics Department, Bandung Institute of Technology, Bandung, Indonesia
c Center for Science and Technology of Advanced Materials, National Nuclear Energy Agency, Kawasan Puspiptek Setu, South Tangerang, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© (2015) Trans Tech Publications, Switzerland.Treatment for bone cancer has begun to be experimented with ferrimagnetic for magnetic induction hyperthermia. On the other hand, composites of bioceramics and biopolymer have been studied for scaffold as these materials resemble the structure of bone. The current study investigated the magnetization of calcium aluminum ferrite magnetic (CaAl4Fe8O19) incorporated in carbonate apatite, alginate and chitosan, that serves as a scaffold. CaAl4Fe8O19 powder were synthesized using calcium nitrate, aluminium nitrate and ferrous chloride using the sol-gel method. Combining the carbonate apatite/chitosan/alginate compoiste and CaAl4Fe8O19 using the freeze-dry method has produced carbonate apatite/alginate/chitosan/ CaAl4Fe8O19 composite scaffolds. The CaAl4Fe8O19 powder and the scaffolds were observed using SEM (scanning electrone microscope) and their magnetization were measured using VSM (vibrating sample magnetometer). It was shown that the scaffold is a composite structure of CaAl4Fe8O19 particles, having diameter ranging from 0.5 to 2 μm, embedded in the pore walls of the carbonate apatite/alginate/chitosan matrix. The saturation magnetization Ms and remanence magnetization Mr of the CaAl4Fe8O19 particles were 20 and 2.0 emu/g, whereas, those of the scaffold were 4.3 and 2.0 emu/gr. The addition of the carbonate apatite/alginate/chitosan composite into CaAl4Fe8O19 decreased the fraction and/or magnetic of the CaAl4Fe8O19 particles.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Aluminium nitrates,Calcium nitrate,Carbonate apatite,Composite scaffolds,Ferrous chloride,Hysteresis curve,Magnetic,Vibrating sample magnetometer[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Carbonate apatite,Hysteresis curve,Magnetic,Scaffold[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.4028/www.scientific.net/MSF.827.75[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]