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Diuretic activity of different organs of matoa (Pometia pinnata) extracts and its influence on potassium and sodium levels
Purwidyaningrum I.a, Sukandar E.Y.a, Fidrianny I.a
a School of Pharmacy, Bandung Institute of Technology, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2016, International Journal of Pharmacognosy and Phytochemical Research. All rights reserved.The purpose of this study was to determine diuretic activity of matoa (Pometia pinnata) extracts (leaves, peel, seeds) and its influence on potassium and sodium levels. Each crude drug was extracted by maceration method followed by evaporation using rotary evaporator. Male Wistar rats were divided into 11 groups i.e. furosemide (1.8 mg/ kg bw), control group CMC 0.5%, and matoa extracts (leaves, peel, seeds) each with doses of 50 mg/kg bw, 100 mg/kg bw, 150 mg/kg bw. Rats were placed in metabolic cages. Urine volume was measured for 4 hours. Potassium and sodium levels in urine were determined by using Atomic Absorption Spectrophotometry. The effective dose of ethanolic matoa leaves extract for diuretic activity was 100 mg/kg bw which could increase the excretion of sodium and potassium in the urine of the male Wistar rats.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Diuretic,Matoa (Pometia pinnata),Potassium levels,Sodium levels,Urine volume[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]