[vc_empty_space][vc_empty_space]
Preventive effect of jasmine flower ethanol extract on MSG-high fat diet induced in male wistar rats
Safitri D.a, Christopher W.a
a Department of Pharmacology and Clinical Pharmacy School of Pharmacy, Institut Teknologi Bandung, Bandung, 40132, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2016, International Journal of Pharmacognosy and Phytochemical Research. All rights reserved.Objectives: The study was conducted to determine the activity of jasmine flowers ethanol extract (JFEE) in preventing obesity and obtain its mechanism on obesity model in male Wistar rats. Methods: This study was conducted by administering 2 mg/kg bw of MSG subcutaneously. It was combined with high-fat diet in obtaining obesity model. There were five groups including normal, control, JFEE with a dose of 100 mg/kg bw, JFEE with a dose of 200 mg/kg bw, and Orlistat with a dose of 21.67 mg/kg bw. Results: Administration of JFEE 200 mg/kg bw was able to decrease significantly on parameters: gaining body weight onset, urine index, feces index, food index, serum level of triglycerides (TG), and total fat index compared to the control group. Conclusion: JFEE with a dose of 200 mg/kg bw through this study was possibly effective in preventing weight gain and fat accumulation by preventing lipid absorption, besides diuretic effect and suppressing appetite.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]High-fat diet,Jasmine flowers,MSG,Obesity[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]