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A multicenter surveillance and reporting of antimicrobial resistance: Focus on Ceftriaxone-resistant Escherichia coli in the year 2012 and 2013

Wikaningtyas P.a, Sukandar E.Y.a, Retnoningrum D.S.a, Parwati I.b

a Pharmacology and Clinical Pharmacy Department, School of Pharmacy, Institut Teknologi Bandung, Bandung, 40132, Indonesia
b Clinical Pathologist, Hasan Sadikin Hospital, Bandung, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2016, International Journal of Pharmaceutical and Clinical Research. All rights reserved.Introduction: Bacterial resistance to commonly prescribed antibiotics is increasing both in developing and developed countries. Resistance to more potent antimicrobial agents has also emerged. The present study aims to report information concerning Escherichia coli resistance to ceftriaxone from clinical specimens from three hospitals in Bandung, Indonesia. Method: A total of 234 specimens in 2012 and 601 specimens in 2013 were collected from all three hospitals. The results were processed to obtain the profile prevalence ceftriaxone-resistant E. coli and the distribution on infected specimens. Result: Increasing number of ceftriaxone-resistant E. coli were observed in two hospitals, hospital A from 35.38% to 43.02% and hospital C from 43.9% to 52.6%. The source of clinical specimen of E. coli resistant to ceftriaxone was varied in all hospital. In hospital A, pus and faeces were the predominant infected specimens. Meanwhile in hospital B, sputum was the predominant infected specimen, and in hospital C urine was the most common specimen infected by ceftriaxone-resistant E. coli. Conclusion: The high and increasing rate of ceftriaxone-resistant E. coli indicate that it is imperative to rationalize the use of antimicrobials in hospitals, use them prudently and also mandate our attention, and periodic monitoring of the trend of the resistance is crucial. A team-based approach to patient care is needed between pharmacist and prescriber to combat antibiotic resistance.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Ceftriaxone,E. coli,Hospital,Resistant,Specimen[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]