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Anredera cordifolia leaves fraction as an antihyperlipidemia
Lestari D.a, Sukandar E.Y.a, Fidrianny I.a
a Pharmacology-Clinical Pharmacy Research Group, School of Pharmacy, Bandung Institute of Technology, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2016 The Authors. Published by Innovare Academic Sciences Pvt Ltd.Objective: The objective of this research was to evaluate the reduction of blood cholesterol level by fraction extracts of binahong (Anredera cordifolia) on male Wistar rats. Methods: The rats were given high-fat food every day for 3 months and pure cholesterol on week 0, 3, 7, and 11. After that, each binahong fraction (n-hexane fraction, ethyl acetate fraction, and water fraction) with doses of 50 mg/kg bw, 100 mg/kg bw, and 200 mg/kg bw was given orally for 3 weeks and observed for lipid profile on day 21. Results: The result showed that n-hexane, ethyl acetate, and water fractions of binahong leaves decreased total cholesterol, triglyceride, and low-density lipoprotein (LDL) level and did not influence the high-density lipoprotein (HDL) level. Meanwhile, statin decreased total cholesterol, triglyceride, and LDL level and increased HDL level. Conclusion: Ethyl acetate fraction of binahong leaves significantly reduced total cholesterol level, triglycerides, and LDL level compared to the negative control group (p<0.05) and had no influence in HDL level.[/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Author keywords" size="size-sm" text_align="text-left"][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Indexed keywords" size="size-sm" text_align="text-left"][vc_column_text]Anredera cordifolia,Cardiovascular,Cholesterol[/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Funding details" size="size-sm" text_align="text-left"][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="DOI" size="size-sm" text_align="text-left"][vc_column_text]https://doi.org/10.22159/ajpcr.2016.v9i6.13628[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]