[vc_empty_space][vc_empty_space]
Reactive oxygen species and aging mechanism
Widowati W.a, Noverina R.b, Ayuningtyas W.b, Kurniawan D.b, Faried A.c, Laksmitawati D.R.d, Rihibiha D.D.e, Rizal R.e, Suciati T.f, Sumitro S.B.g
a Faculty of Medicine, Maranatha Christian University, Bandung, West Java, Indonesia
b Laboratory of Animal and Stem Cells, PT Bio Farma (Persero), Bandung, West Java, Indonesia
c Neurosurgery Department, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia
d Faculty of Pharmacy, University of Pancasila, Jakarta, Indonesia
e Aretha Medika Utama, Biomolecular and Biomedical Research Centre, Bandung, West Java, Indonesia
f School of Pharmacy, Bandung Institute of Technology, Bandung, West Java, Indonesia
g Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Malang, East Java, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2018 Nova Science Publishers, Inc. All rights reserved.Skin aging is a complex process affected by both genetic and environmental factors, and it is caused by the cumulative damage from exposure to ultraviolet (UV) radiation. Chronic exposure to UV radiation on human skin further generates solar elastosis, degradation of the extracellular matrix (ECM), and wrinkle formation. UV radiation exposure leads to production of reactive oxygen species (ROS) in the skin. Chronological & photo-aging occurred via ROS by cascade signaling pathways. Treatment of antioxidants is an effective approach to prevent symptoms related to photo-induced skin aging. In this chapter, the mechanisms of ROS generation in the skin, the roles of ROS in altering the skin and ROS elimination in the body are discussed.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]