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Design of Pyrrolic-N-Rich Carbon Dots with Absorption in the First Near-Infrared Window for Photothermal Therapy
Permatasari F.A.a, Fukazawa H.a, Ogi T.a, Iskandar F.b, Okuyama K.a
a Department of Chemical Engineering, Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima, 739-8527, Japan
b Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, 40132, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]Copyright © 2018 American Chemical Society.Pyrrolic-N-rich carbon dots (CDs) that exhibit an absorption peak in the first near-infrared (NIR) window region were developed using a one-step microwave-assisted hydrothermal synthesis. A high concentration of urea enabled the introduction of a large amount of pyrrolic-nitrogen on the CD surfaces. Upon optimization of the experimental conditions, the absorption peak of the CDs red-shifted from 550 to 650 nm. The resulting pyrrolic-N-rich CDs exhibited photothermal effects with high NIR photothermal efficiency (54.3%) and photoluminescence. The prepared CDs, which show a first NIR window absorption peak, photoluminescence, and negative surface charge, have the potential to be used as multifunctional nanocarriers for cell imaging and drug delivery and as photothermal agents in cancer therapy. ©[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Carbon dots,Experimental conditions,Microwave-assisted hydrothermal synthesis,Multi-functional nanocarriers,Near Infrared,Negative surface charges,Photo-thermal,Pyrrolic nitrogen[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]carbon dots,first near-infrared window absorption,photoluminescence,photothermal,pyrrolic-nitrogen[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.1021/acsanm.8b00497[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]