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Polyvinylpyrrolidone/cellulose acetate nanofibers synthesized using electrospinning method and their characteristics

Jauhari J.a, Wiranata S.a, Rahma A.b, Nawawi Z.a, Sriyanti I.a

a Laboratory of Instrumentation and Nanotechnology Applications, Faculty of Computer Science, Universitas Sriwijaya, Palembang, Indonesia
b Pharmaceutics Department, Institut Teknologi Bandung, Bandung, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2019 IOP Publishing Ltd.Polyvinylpyrrolidone (PVP) is among the most extensively used polymer in electrospinning. It has excellent electrospinnabibilty, aqueous solubility, and biocompatibility. PVP has demonstrated potential application as drug delivery matrix and wound dressing material. However, PVP is easily degraded in the presence of moisture/water. Incorporation of cellulose acetate (CA) in PVP nanofiber is a promising way to increase of resistance to water. The objective of this study was to prepare to PVP/CA nanofiber by electrospinning method and to determine their characteristics. The SEM result shows that electrospinning of PVP/CA solution at 5% concentration (FC1) resulted in beaded fiber. At 10% (FC2) and 15% (FC3) concentration, the resulted PVP/CA fibers were bead-free. The average diameter of FC1-, FC2-, and FC3 were 258, 398, 534 nm, respectively. The FTIR analysis confirmed the presence of PVP and CA in FC1-, FC2- and FC3 nanofiber as indicated by characteristic peaks of hydroxyl groups and cyclic amides (PVP); and alkane and carboxyl groups (CA). The XRD study revealed amorphous state of PVP nanofiber and crystallinity state of CA nanofiber. The mechanical test showed that electrospun fiber with smaller diameter had greater tensile strength. The presence of CA increased the functional properties of PVP-based nanofiber.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Aqueous solubility,Cellulose acetates,Characteristic peaks,diameter,Electrospinning method,Functional properties,Poly vinyl pyrrolidone,Wound dressing materials[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]cellulose acetate,diameter,morphology,nanofiber,polyvinylpyrrolidone[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text]Jaidan Jauhari Sendi Wiranata Annisa Rahma Zainuddin Nawawi Ida Sriyanti Jaidan Jauhari Sendi Wiranata Annisa Rahma Zainuddin Nawawi Ida Sriyanti Laboratory of Instrumentation and Nanotechnology Applications, Faculty of Computer Science, Universitas Sriwijaya, Palembang, Indonesia Department of Physics Education, Faculty of Education, Universitas Sriwijaya, Palembang, Indonesia Pharmaceutics Department, Institut Teknologi Bandung, Bandung, Indonesia Department of Electrical Engineering, Universitas Sriwijaya, Palembang, Indonesia Jaidan Jauhari, Sendi Wiranata, Annisa Rahma, Zainuddin Nawawi and Ida Sriyanti 2019-06-01 2019-03-22 13:09:32 cgi/release: Article released bin/incoming: New from .zip yes Polyvinylpyrrolidone (PVP) is among the most extensively used polymer in electrospinning. It has excellent electrospinnabibilty, aqueous solubility, and biocompatibility. PVP has demonstrated potential application as drug delivery matrix and wound dressing material. However, PVP is easily degraded in the presence of moisture/water. Incorporation of cellulose acetate (CA) in PVP nanofiber is a promising way to increase of resistance to water. The objective of this study was to prepare to PVP/CA nanofiber by electrospinning method and to determine their characteristics. The SEM result shows that electrospinning of PVP/CA solution at 5% concentration (FC1) resulted in beaded fiber. At 10% (FC2) and 15% (FC3) concentration, the resulted PVP/CA fibers were bead-free. The average diameter of FC1-, FC2-, and FC3 were 258, 398, 534 nm, respectively. The FTIR analysis confirmed the presence of PVP and CA in FC1-, FC2- and FC3 nanofiber as indicated by characteristic peaks of hydroxyl groups and cyclic amides (PVP); and alkane and carboxyl groups (CA). The XRD study revealed amorphous state of PVP nanofiber and crystallinity state of CA nanofiber. The mechanical test showed that electrospun fiber with smaller diameter had greater tensile strength. 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