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Synthesis and Characterization of Rotary Forcespun Polyvinylpyrrolidone Fibers Loaded by Garlic (Allium sativum) Extract
Zahra F.a, Fauzi A.a, Miftahul Munir M.a, Khairurrijal K.a
a Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Bandung, 40132, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© Published under licence by IOP Publishing Ltd.Garlic (Allium sativum) is one of the plants traditionally used for food supplement, natural medicine, and a food flavoring. Garlic has been proven to exhibit many important pharmacological activities that bring benefits for human health such as antioxidant, antimicrobial, antithrombotic, antihypertensive, cancer prevention, and lipid-lowering effects. However, the organosulfur compounds that contribute the previously mentioned activities have a high rate of degradability. In this paper, composite fibers of garlic extract encapsulated in polyvinylpyrrolidone (PVP) fibers are reported. The fibers were synthesized using the rotary forcespinning technique to protect organosulfur compounds from degradation and to maintain their antioxidant properties. The precursor solution was prepared by mixing 15% PVP in 50% ethanol (w/w) with garlic extract (GAE) in the ratio of 10:1, 10:3, and 10:5 (w/w). Microscopy images showed that the average diameter of fibers increases with increasing viscosity, which was the result of the higher polymer-to-extract ratio. All the fibers had smooth surfaces with no beads. The coefficient of variance (CV) of each fibers distribution was lower than 0.3, which marks the uniformity of the fibers formed. Analyses of the Fourier Transform Infrared (FT-IR) spectra proved some peak differences between the PVP fibers and the PVP fibers loaded with GAE, one of them is the peak at wavenumber 1034 cm-1 indicating the presence of sulfoxide functional groups.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Antioxidant properties,Coefficient of variance,Fourier transform infrared,Lipid-lowering effects,Organosulfur compounds,Pharmacological activity,Polyvinyl pyrrolidone,Synthesis and characterizations[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text]This research was financially supported by Directorate of Research and Community Engagement of Ministry of Research, Technology, and Higher Education, the Republic of Indonesia under the University’s Excellence Research (PUPT) Grant in the fiscal year 2018.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.1088/1757-899X/515/1/012005[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]