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Updates on 4-hydroxyderricin and xanthoangelol of angelica plants: Extraction and pharmacological activities

Aulifa D.L.a,b, Adnyana I.K.a, Sukrasnoa, Levita J.c

a Pharmaceutical Biology Research Group, School of Pharmacy, Bandung Institute of Technology, Bandung, 40132, Indonesia
b Department of Pharmaceutical Biology, Indonesian School of Pharmacy (Sekolah Tinggi Farmasi Indonesia), Bandung, 40226, Indonesia
c Department of Pharmacology and Clinical Pharmacy Faculty of Pharmacy, Universitas Padjadjaran, 45363, Indonesia

[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© RASĀYAN. All rights reserved.Two chalcones, e.g. 4-hydroxyderricin and xanthoangelol, have been proven in revealing many potential pharmacological activities, therefore their extraction method is critical because it influences the yield and, furthermore, its pharmacological activities. This review highlights the extraction method and various pharmacological activities of 4-hydroxyderricin and xanthoangelol from Angelica keiskei plants. The chalcone’s diverse pharmacological activities are attributed to the flexible conformation of the opened-C ring and the moderate lipophilicity character on the A aromatic ring. The presence of a double bond in conjugation with carbonyl moiety is also important. However, further explorations need to be performed to obtain a remarkable yield of these particular prenylated-compounds and to understand their mechanisms of actions.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]4-Hydroxyderricin,Angelica keiskei,Chalcones,Xanthoangelol[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.31788/RJC.2020.1315397[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]