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Kurzichalcolactone A and B, two chalcone derivatives from Indonesian Cryptocarya
Kurniadewi F.a, Nurjayadi M.a, Kartika I.R.a, Hakim E.H.b, Juliawaty L.D.b, Syah Y.M.b
a Department of Chemistry, Mathematics and Science Faculty, Universitas Negeri Jakarta, Indonesia
b Department of Chemistry, Bandung Institute of Technology, Bandung, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© Published under licence by IOP Publishing Ltd.Kurzichalcolactone A (1) and B (2), two chalcone derivatives were isolated from two species of Indonesian Cryptocarya: Cryptocarya phoebeopsis and Cryptocarya morotaiense. The structures of the isolated compounds were elucidated based on the analysis of spectroscopic data, including UV, IR, NMR, and mass spectra. On biological evaluation of these compounds for their cytotoxic activity, it was found that (1) exhibited moderate inhibition activities against murine leukemia P388 cells while (2) was inactive.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Biological evaluation,Chalcone derivatives,Cytotoxic activities,Inhibition activity,Isolated compounds,Mass spectra,Spectroscopic data[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text]Part of this study was supported by research grant of PDUPT KEMENRISTEKDIKTI 2019-2020 with the contract number: 3/SP2H/DRPM/LPPM-UNJ/III/2019.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.1088/1742-6596/1402/5/055081[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]