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Two stilbenes from Indonesian Cassia grandis and their antibacterial activities
Kusumaningtyas V.A.a,b, Syah Y.M.b, Juliawaty L.D.b
a Department of Chemistry, Faculty of Science and Informatics, Universitas Jenderal Achmad Yani, Cimahi, 40285, Indonesia
b Natural Product Chemistry Group, Faculty of Mathematics and Natural Sciences, Institut Tenologi Bandung, Bandung, 40132, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2020 World Research Association. All rights reserved.Cassia grandis is an ornamental plant that has been reported to have ethnopharmacological uses to heal wounds, scabies and other skin medications in Indonesian traditional medicine. Phytochemical investigation of the heartwood C. grandis led to the isolation of two known stilbenes: piceatannol 1 and resveratrol 2 isolated from the methanol extract. The structures were established on the basis of chemical evidence and spectroscopic methods, especially NMR as well as by comparing with published data. The antibacterial activity was carried out by using broth microdilution method and evaluated against two pathogenic bacteria: Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922. One of the isolated compounds 1 was reported as secondary metabolite of Indonesian C. grandis. Compound 2 exhibited promising selective antibacterial potent against Escherichia coli ATCC 25922.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Antibacterial,Cassia grandis,Piceatannol,Resveratrol,Stilbenes[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text]We are thankful to Ministry of Research, Technology and Higher Education Republic Indonesia and LPPM Universitas Jenderal Achmad Yani for financial support.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text][/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]