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Non-Enzymatic Electrochemical Detection for Uric Acid Based on a Glassy Carbon Electrode Modified with MOF-71
Abrori S.A.a, Septiani N.L.W.a, Hakim F.N.a, Maulana A.a, Suyatmana, Nugrahaa, Anshori I.a, Yuliarto B.a
a Engineering Physics Department, Faculty of Industrial Technology, Advanced Functional Materials Laboratory, Bandung Institute of Technology, Bandung, 40132, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2001-2012 IEEE.The development of non-noble-metal sensing material for sensitive and selective detection of uric acid with a simple material synthesis technique has not been frequently reported in recent years. Taking advantage of the unique properties of highly porous materials of Metal-Organic Frameworks, which incomparable in their structural diversity and tunability as well as their range of chemical and physical properties, open up a chance for developing novel nanomaterial for electrochemical sensor applications. In this article, we evaluated MOF-71 as a sensing material on a glassy carbon electrode (GCE) in a three-electrode system for electrochemical detection of uric acid. The MOF-71 was synthesized by a simple solvothermal method. Its structural characteristics that are examined by scanning electron microscopy and X-ray diffraction confirmed the successful formation of MOF-71. Cyclic voltammetry (CV) and differential pulse voltammetry DPV) analysis showed the successful uric acid detection in a phosphate buffer solution and showed good electrochemical catalytic activity toward uric acid. DPV was selected for the determination of uric acid with a sensitivity of 0.4811 mA.mM-1.cm-2, the detection range of 50.0- 1000 μ M , and detection limit of 15.61 μ M at an S/N = 3.[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Author keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Chemical and physical properties,Differential pulse voltammetry,Electrochemical catalytic activities,ELectrochemical detection,Glassy carbon electrodes,Highly porous materials,Phosphate buffer solutions,Structural characteristics[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Indexed keywords” size=”size-sm” text_align=”text-left”][vc_column_text]Electrochemical,MOF-71,non-enzymatic,uric acid[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”Funding details” size=”size-sm” text_align=”text-left”][vc_column_text]Manuscript received June 25, 2020; revised July 30, 2020; accepted July 31, 2020. Date of publication August 5, 2020; date of current version December 4, 2020. This work was supported in part by the Ministry of Education and Culture and Ministry of Research and Technology through the Grant Scheme of the World Class University (WCU) Program managed by the Institut Teknologi Bandung, in part by the Institut Teknologi Bandung, Indonesia, and in part by the Ministry of Education and Culture and Ministry of Research and Technology, Indonesia. The associate editor coordinating the review of this article and approving it for publication was Prof. Diego Barrettino. (Corresponding author: Brian Yuliarto.) Syauqi Abdurrahman Abrori, Ni Luh Wulan Septiani, Fahmi Nur Hakim, Angga Maulana, and Suyatman are with the Advanced Functional Materials Laboratory, Engineering Physics Department, Faculty of Industrial Technology, Bandung Institute of Technology, Bandung 40132, Indonesia (e-mail: brian@tf.itb.ac.id).[/vc_column_text][vc_empty_space][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][vc_empty_space][megatron_heading title=”DOI” size=”size-sm” text_align=”text-left”][vc_column_text]https://doi.org/10.1109/JSEN.2020.3014298[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]