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The effect of aerobic exercises on cognition, physical fitness, and apolipoprotein E plasma among women with mild cognitive impairment
Fitriana L.A.a, Putri S.T.a, Anggadiredja K.b, Theresa R.M.c, Adnyana I.K.b
a Department of Nursing, Faculty of Sport Sciences and Health Education, Universitas Pendidikan Indonesia, Bandung, Indonesia
b Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, Institut Teknologi Bandung, Bandung, Indonesia
c Department of Psychiatry, Faculty of Medicine, Universitas Pembangunan Nasional Veteran Jakarta, Jakarta, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]© 2020, Advanced Scientific Research. All rights reserved.Aerobic exercise is believed to improve cognition and physical fitness, but its effect on Apolipoprotein E plasma levels in humans is quiet limited. The purpose of this study was to analyze the effect of aerobic exercises on cognition, physical fitness, and Apolipoprotein E plasma among women with mild cognitive impairment (MCI). This study used the quasy experiment with the pre and post-test method with control group. The participant of the study included 32 women aged 44-61 years with MCI. They were divided into two groups; aerobic exercises group (2×60 minutes/week, n = 16) and control group (n = 16). The intervention was carried out for 16 weeks. The inclusion criteria of this study is those who had MoCa-Ina test score ≤ 26, had good vision and hearing, did not have severe illness, and did not exercise at least 3 months before the experimentation. The results showed that aerobic exercises can improve memory (p = 0.002), improve one-leg balance with open eyes (p <0.001), one-leg balance with closed eyes (p = 0.017), and lower extremity strength (p = 0.001), and reduce Apolipoprotein E plasma significantly (p =0.001) in women with mild cognitive impairment. In conclusion, aerobic exercises could have positive effect on memory, physical fitness, and Apolipoprotein E plasma levels in MCI women. Further studies can be conducted regarding to the effects of aerobic exercise in older adults w ith dementia.[/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Author keywords" size="size-sm" text_align="text-left"][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Indexed keywords" size="size-sm" text_align="text-left"][vc_column_text]Aerobic exercise,Apolipoprotein E,Cognition,Mild cognitive impairment,Physical fitness[/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Funding details" size="size-sm" text_align="text-left"][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="DOI" size="size-sm" text_align="text-left"][vc_column_text]https://doi.org/10.31838/ijpr/2020.12.01.268[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]