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Antioxidant activity and total phenolic content of endophytic fungus fennellia Nivea NRRL 5504
Saraswaty V.a, Srikandace Y.a, Simbiyani N.A.b, Jasmansyahb, Setiyanto H.c, Udin Z.a
a Research Centre for Chemistry, Indonesian Institute of Sciences, Indonesia
b Department of Chemistry, University of Jenderal Ahmad Yani, Indonesia
c Analytical Chemistry Research Group, Institute of Technology Bandung, Indonesia
[vc_row][vc_column][vc_row_inner][vc_column_inner][vc_separator css=”.vc_custom_1624529070653{padding-top: 30px !important;padding-bottom: 30px !important;}”][/vc_column_inner][/vc_row_inner][vc_row_inner layout=”boxed”][vc_column_inner width=”3/4″ css=”.vc_custom_1624695412187{border-right-width: 1px !important;border-right-color: #dddddd !important;border-right-style: solid !important;border-radius: 1px !important;}”][vc_empty_space][megatron_heading title=”Abstract” size=”size-sm” text_align=”text-left”][vc_column_text]Antioxidant is an interesting bioactivity since it has several correlations with disease such as Alzheimer, cancer, ageing and many others in which were promoted by free radicals. Investigation on our endophytic fungus collection namely Fennelia nivea NRRL 5504 revealed that the fermented medium has antioxidant property against DPPH through free radical scavenging effect. Fermentation in liquid medium i.e. Potatoes Dextrose Broth, resulted that the fermented medium reached about 86.51% (p<0.05) of free radical inhibition on the eighth day. Results of phytochemical screening from extracted fermentation medium showed the presence of terpenes, triterpenes, phenolic compound, tannin, flavonoid and also saponin. The highest antioxidant activity was showed by ethyl acetate extract. Calculation on total phenolic content of ethyl acetate crude extract was 0.544 mg g-1 equivalent to pyrogallol. By exposure above, we have alternative source of antioxidant that came from our endophytic fungus collection which we isolated previously from Typhonium divaricatum Lodd. © 2013 Asian Network for Scientific Information.[/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Author keywords" size="size-sm" text_align="text-left"][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Indexed keywords" size="size-sm" text_align="text-left"][vc_column_text]Antioxidant,Endophytic,Fennelia nivea,Fungus[/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="Funding details" size="size-sm" text_align="text-left"][vc_column_text][/vc_column_text][vc_empty_space][vc_separator css=".vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}"][vc_empty_space][megatron_heading title="DOI" size="size-sm" text_align="text-left"][vc_column_text]https://doi.org/10.3923/pjbs.2013.1574.1578[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/4″][vc_column_text]Widget Plumx[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row][vc_column][vc_separator css=”.vc_custom_1624528584150{padding-top: 25px !important;padding-bottom: 25px !important;}”][/vc_column][/vc_row]